In clinical care of IBD patients, the detection of colitis-associated dysplasia or cancer (CAD or CAC) is a rising issue for long standing ulcerative colitis (UC) or colonic Crohn’s disease (CD). The risk of colorectal cancer increased 8-10 years after the onset of symptoms in UC patients. From the current international guidelines, dye spraying chromoendoscopy with targeted biopsy was recommended for colonoscopy surveillance of CAC. However, conventional dye spraying chromoendoscopy is time cons